On June 1, 2018, Zhu, Cheng-Liang; Wang, Cheng; Qin, Qi-Xue; Yruegas, Sam; Martin, Caleb D.; Xu, Hao published an article.Related Products of 109660-12-0 The title of the article was Iron(II)-Catalyzed Azidotrifluoromethylation of Olefins and N-Heterocycles for Expedient Vicinal Trifluoromethyl Amine Synthesis. And the article contained the following:
We report herein an iron-catalyzed azidotrifluoromethylation method for expedient vicinal trifluoromethyl primary-amine synthesis. This method is effective for a broad range of olefins and N-heterocycles, and it facilitates efficient synthesis of a wide variety of vicinal trifluoromethyl primary amines, including those that prove difficult to synthesize with existing approaches. Our preliminary mechanistic studies revealed that the catalyst-promoted azido-group transfer proceeds through a carbo-radical instead of a carbocation species. Characterization of an active iron catalyst through X-ray crystallog. studies suggests that in situ generated, structurally novel iron-azide complexes promote the oxidant activation and selective azido-group transfer. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Related Products of 109660-12-0
The Article related to trifluoromethyl primary amine preparation, olefin azidotrifluoromethylation iron catalyst, n-heterocycles, azides, iron catalysis, olefins, trifluoromethyl amines, General Organic Chemistry: Synthetic Methods and other aspects.Related Products of 109660-12-0