Zhu, Yi-Ming; Fang, Yizhan; Li, Haiyan; Xu, Xiao-Ping; Ji, Shun-Jun published an article in 2021. The article was titled 《Divergent Reaction of Isocyanides with o-Bromobenzaldehydes: Synthesis of Ketenimines and Lactams with Isoindolinone Cores》, and you may find the article in Organic Letters.Quality Control of 2-Bromonicotinaldehyde The information in the text is summarized as follows:
A divergent reaction of isocyanides RNC (R = tert-Bu, cyclohexyl, adamantyl, etc.) with o-bromobenzaldehydes such as 2-bromo-4,5-dimethoxybenzaldehyde, 6-bromo-2H-1,3-benzodioxole-5-carbaldehyde, 2-bromopyridine-3-carbaldehyde for the synthesis of isoindolinone-derived ketenimines such as I and lactams such as II was disclosed. The reaction features readily available reactants, relatively mild conditions, and high yields of products. Ketenimines could be applied in further transformations for access to other functional mols. A mechanism study showed that the palladium-migration/imine-insertion process was the key step in this reaction. In the experimental materials used by the author, we found 2-Bromonicotinaldehyde(cas: 128071-75-0Quality Control of 2-Bromonicotinaldehyde)
2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Quality Control of 2-Bromonicotinaldehyde