A novel photoredox-active group for the generation of fluorinated radicals from difluorostyrenes was written by Zubkov, Mikhail O.;Kosobokov, Mikhail D.;Levin, Vitalij V.;Kokorekin, Vladimir A.;Korlyukov, Alexander A.;Hu, Jinbo;Dilman, Alexander D.. And the article was included in Chemical Science in 2020.Formula: C5F5N The following contents are mentioned in the article:
A 4-tetrafluoropyridinylthio group was suggested as a new photoredox-active moiety. The group could be directly installed on difluorostyrenes in a single step by the thiolene click reaction. It proceeded upon visible light catalysis with 9-phenylacridine providing various difluorinated sulfides as radical precursors. Single electron reduction of the C-S bond with the formation of fluoroalkyl radicals was enabled by the electron-poor azine ring. The intermediate difluorinated sulfides were involved in a series of photoredox reactions with silyl enol ethers, alkenes, nitrones and an alkenyl trifluoroborate. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Formula: C5F5N).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six 蟺 electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H眉ckel criteria for aromatic systems. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Formula: C5F5N